Translational Research in Atrial Fibrillation

Translational research in atrial fibrillation: a quest for mechanistically based diagnosis and therapy.

The European Network for Translational Research in Atrial Fibrillation (EUTRAF): objectives and initial results.

Atrial fibrillation (AF) is the most common sustained arrhythmia in the general population. As an age-related arrhythmia AF is becoming a huge socio-economic burden for European healthcare systems. Despite significant progress in our understanding of the pathophysiology of AF, therapeutic strategies for AF have not changed substantially and the major challenges in the management of AF are still...

Almanac 2015: atrial fibrillation research in Heart

Atrial fibrillation continues to attract interest in the cardiovascular community and in Heart Over 60 original research and review papers published in Heart in 2014-2015 cover various aspects of atrial fibrillation, from associated conditions and precipitating factors to new approaches to management. Here, we provide an overview of articles on atrial fibrillation published in Heart in 2014-201...

Pathophysiological mechanisms of atrial fibrillation: a translational appraisal.

Atrial fibrillation (AF) is an arrhythmia that can occur as the result of numerous different pathophysiological processes in the atria. Some aspects of the morphological and electrophysiological alterations promoting AF have been studied extensively in animal models. Atrial tachycardia or AF itself shortens atrial refractoriness and causes loss of atrial contractility. Aging, neurohumoral activ...

American Heart Association Atrial Fibrillation Research Summit

N.A. Mark Estes III, MD, FAHA, Chair; Ralph L. Sacco, MS, MD, FAHA; Sana M. Al-Khatib, MD, MHS; Patrick T. Ellinor, MD, PhD, FAHA; Judy Bezanson, DSN, CNS, RN; Alvaro Alonso, MD, MPH; Charles Antzelevitch, PhD, FAHA; Randall G. Brockman, MD; Peng-Sheng Chen, MD; Sumeet S. Chugh, MD, FAHA; Anne B. Curtis, MD, FAHA; John P. DiMarco, MD, PhD; Kenneth A. Ellenbogen, MD, FAHA; Andrew E. Epstein, MD,...